GENETICS AND GENOMICS JOURNAL
Designation: Independent Research Group Leader
Department: Max Planck Institute for Biology of Ageing
University: University of Cologne
Martin Sebastian completed a degree in Human Biology from the Philipps-University in Marburg, Germany, where I focused on cell biology and biochemistry. During this time, I also completed industrial internships and rotations in academic labs in USA and then moved on to San Diego, CA, USA, where he was trained in neurobiology and vascular biology, and further focused on cardiac physiology to obtain the Ph.D. degree. In 2010, he was moved to the Max Planck Institute for Biology of Ageing in Cologne, Germany, for his postdoctoral training with Adam Antebi. During this time, Martin Sebastian performed genetic screens in the nematode C. elegans and identified a novel longevity pathway. In 2014, he is became an independent group leader at the Max Planck Institute for Biology of Ageing, with support from an ERC starting grant. Martin Sebastian laboratory focuses on the metabolic and genetic regulation of ageing using an interdisciplinary approach based on work with nematodes, cultured cells, and mice.
His research interest is focused on ageing is a complex process that is influenced by an organism’s genetic makeup and its environment. A number of biological quality control processes become faulty with age, and one of these is protein quality control. Proteins are the "molecular machines" in all cells. genetic screening approaches, analyzing the role of this pathway in depth using mammalian cells and mice.
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